Alanine Aminotransferase (ALT)

Liver-specific enzyme released when hepatocytes are damaged.

Units

U/L

Reference (Male)

7 – 55 U/L

Reference (Female)

7 – 45 U/L

Aliases

SGPT

What it measures

Liver-specific enzyme released when hepatocytes are damaged.

What a high value can mean

Fatty liver, viral hepatitis, alcohol, drug toxicity (acetaminophen, statins).

What a low value can mean

Generally not clinically significant on its own.

Conditions it helps assess

Liver injury
Hepatitis
NAFLD

Reading these numbers in context

Reference ranges describe the central 95 % of a healthy reference population — 5 % of perfectly healthy people fall outside any given range by definition. A single mildly abnormal value is rarely meaningful on its own. blood-test.life always interprets values together with related biomarkers before flagging.

Related biomarkers in Liver Panel

Aspartate Aminotransferase AST Found in liver, heart, and muscle. AST/ALT ratio (De Ritis) > 2 suggests alcoholic liver disease. Alkaline Phosphatase ALP Enzyme from liver, bone, intestine, and placenta. Rises in biliary obstruction or bone turnover. Total Bilirubin TBIL Byproduct of red cell breakdown. Elevation causes jaundice.